| 2024-02 |
Anticancer Evaluation of Novel Benzofuran–Indole Hybrids as Epidermal Growth Factor Receptor Inhibitors against Non-Small-Cell Lung Cancer Cells |
Pharmaceuticals
|
| 2024-01 |
Catalyst-free assembly of a polyfunctionalized 1,2,4-triazole-fused N-heterocycle, 6-acylated pyrrolo[1,2-a][1,2,4]triazolo[5,1-c]pyrazine |
Organic and Biomolecular Chemistry
|
| 2024-01 |
Recent advances in the synthesis of N-fused heterocycles from N-aroylmethylpyrrole-2-carboxaldehyde derivatives via annulative functionalization strategies |
Tetrahedron
|
| 2023-12 |
Development of Mitochondria‐Targeting Photosensitizers via Topoisomerase I Inhibition |
Asian Journal of Organic Chemistry
|
| 2023-08 |
Benzo[d]imidazole-pyrrolo[1,2-a]pyrazine Hybrids Ameliorate Amyloid Aggregates in the Brain of Alzheimer Transgenic Mice |
ACS Chemical Neuroscience
|
| 2023-08 |
Regioselective Access to 1,2,4-Triazole-Fused N-Heterocycle, Pyrrolo[1,2-a][1,2,4]triazolo[5,1-c]pyrazine, via Double Dehydrative Cyclizations |
The Journal of Organic Chemistry
|
| 2023-05 |
4-Acyl-3,4-dihydropyrrolo[1,2-a]pyrazine Derivative Rescued the Hippocampal-Dependent Cognitive Decline of 5XFAD Transgenic Mice by Dissociating Soluble and Insoluble A beta Aggregates |
ACS Chemical Neuroscience
|
| 2023-05 |
Divergent synthesis of two types of indolizines from pyridine-2-acetonitrile, (hetero)arylglyoxal, and TMSCN |
Organic and Biomolecular Chemistry
|
| 2023-05 |
C3 Functionalization of indolizines via HFIP-promoted Friedel-Crafts reactions with (hetero)arylglyoxals |
ACS OMEGA
|
| 2023-01 |
Cu-Catalyzed Ullmann-Type Double C-N Coupling Approach to 5-Aryl-5H-indolizino[3,2-b]indoles |
Journal of Organic Chemistry
|
| 2022-11 |
Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models |
Alzheimer's Research and Therapy
|
| 2022-11 |
Synthesis and Biological Evaluation of a Fused Structure of Indolizine and Pyrrolo[1,2-c]pyrimidine: Identification of Its Potent Anticancer Activity against Liver Cancer Cells |
PHARMACEUTICALS
|
| 2022-10 |
Benzofuro[2,3-c]isoquinolines as novel AIEgens: Modulation of AIE characteristics by a single methoxy group |
DYES AND PIGMENTS
|
| 2022-09 |
Regioselective Synthesis of 1-Cyano-3-arylindolizines: Construction of Pyrroles via DDQ-Mediated Ring Closure of Cyclopropyl Pyridines |
Advanced Synthesis and Catalysis
|
| 2022-09 |
Generation of a poly-functionalized indolizine scaffold and its anticancer activity in pancreatic cancer cells |
BIOORGANIC CHEMISTRY
|
| 2022-05 |
VI-116, A Novel Potent Inhibitor of VRAC with Minimal Effect on ANO1 |
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
|
| 2021-12 |
Synthesis of poly-functionalized indolizines via [5+1] annulative access to pyridines |
ADVANCED SYNTHESIS & CATALYSIS
|
| 2021-12 |
Development of a DABCO-Succinic Acid Based Catalytic System for the Aza-Michael Addition and Aza-Michael/Knoevenagel Tandem Reaction of Thiazolidine-2,4-dione to Electron Deficient Alkenes |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2021-11 |
Anti-amyloidogenic indolizino[3,2-: C] quinolines as imaging probes differentiating dense-core, diffuse, and coronal plaques of amyloid-β |
RSC Medicinal Chemistry
|
| 2021-09 |
Diastereoselective synthesis of densely functionalized 3a,8a-dihydro-8H-furo[3,2-a]pyrrolizines through one-pot three-component assembly |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2021-08 |
Michael-aldol double elimination cascade to make pyridines: use of chromone for the synthesis of indolizines |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2021-07 |
One-pot three-component coupling access to 1,2-dihydropyrrolo[1,2-a]pyrazine-1-phosphonates: multi-functionalization of pyrazine unit |
ORGANIC & BIOMOLECULAR CHEMISTRY
|
| 2021-07 |
A regioselective [4+2] annulation approach to 5-acylindolizine-7-carbonitriles: generation of poly-substituted pyridines |
ORGANIC & BIOMOLECULAR CHEMISTRY
|
| 2021-05 |
X-ray crystal structure-guided design and optimization of 7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile scaffold as a potent and orally active monopolar spindle 1 inhibitor |
JOURNAL OF MEDICINAL CHEMISTRY
|
| 2021-04 |
Facile access to 3,4-disubstituted 2H-chromenes via domino [4+2] annulation |
SYNTHESIS-STUTTGART
|
| 2021-03 |
BF3·OEt2-catalyzed one-pot three-component access to diarylmethylazides |
TETRAHEDRON LETTERS
|
| 2021-03 |
Regioselective functionalization of N-fused heteroaromatics via FeCl3-catalyzed nucleophilic addition to activated N-heterocycles |
SYNTHESIS-STUTTGART
|
| 2021-01 |
Fine tuning of the HOMO-LUMO gap of 6-(thiophen-2-yl)indolizino[3,2-c]quinolines and their self-assembly to form fluorescent organic nanoparticles: rational design and theoretical calculations |
ChemPhotoChem
|
| 2021-01 |
Orally Administered Benzofuran Derivative Disaggregated Aβ Plaques and Oligomers in the Brain of 5XFAD Alzheimer Transgenic Mouse |
ACS CHEMICAL NEUROSCIENCE
|
| 2020-12 |
Fluorescent indolizine derivative YI-13 detects amyloid-beta monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model |
PLOS ONE
|
| 2020-12 |
Expansion of diazepine heterocyclic chemical space via sequential Knoevenagel condensation-intramolecular aza-Wittig reaction: 2-acyl-4-aryl-5H-pyrrolo[1,2-d][1,4]diazepines |
ORGANIC & BIOMOLECULAR CHEMISTRY
|
| 2020-12 |
One-pot four-component coupling approach to polyheterocycles: 6H-furo[3,2-f]pyrrolo[1,2-d][1,4]diazepine |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2020-10 |
One-pot access to 2-amino-3-arylbenzofurans: direct entry to polyheterocyclic chemical spaces |
ORGANIC & BIOMOLECULAR CHEMISTRY
|
| 2020-10 |
Solvent-Controlled Divergent Syntheses of Polycyclic N-Fused Heteroaromatics |
SYNTHESIS-STUTTGART
|
| 2020-09 |
Expanding the chemical space: discovery of new anticancer 3-arylbenzofuran derivatives |
JOURNAL OF HETEROCYCLIC CHEMISTRY
|
| 2020-08 |
Domino [4 + 2] Annulation Access to Quinone−Indolizine Hybrids: Anticancer N‑Fused Polycycles |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2020-08 |
6-(Hetero)arylindolizino[1,2-c]quinolines as highly fluorescent chemical space: synthesis and photophysical properties |
JOURNAL OF HETEROCYCLIC CHEMISTRY
|
| 2020-08 |
Diversity-oriented generation and biological evaluation of new chemical scaffolds bearing a 2,2-dimethyl-2H-chromene unit: Discovery of novel potent ANO1 inhibitors |
BIOORGANIC CHEMISTRY
|
| 2020-05 |
A domino annulation approach to 3,4-diacylpyrrolo[1,2-a]pyrazines: decoration of pyrazine units |
ORGANIC & BIOMOLECULAR CHEMISTRY
|
| 2020-04 |
Dual-functioning IQ-LVs as lysosomal viscosity probes with red-shifted emission and inhibitors of autophagic flux |
SENSORS AND ACTUATORS B-CHEMICAL
|
| 2020-02 |
Facile approach to benzo[d]imidazole-pyrrolo[1,2-a]pyrazine hybrid structures through double cyclodehydration and aromatization and their unique optical properties with blue emission |
RSC ADVANCES
|
| 2020-02 |
Expansion of chemical space based on a pyrrolo[1,2-a]pyrazine core: synthesis and its anticancer activity in prostate cancer and breast cancer cells |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
|
| 2019-10 |
Novel turn-on fluorescent biosensors for selective detection of cellular Fe3+ in lysosomes: Thiophene as a selectivity-tuning handle for Fe3+ sensors |
DYES AND PIGMENTS
|
| 2019-06 |
Fluorescent 1,4-naphthoquinones to visualize diffuse and dense-core amyloid plaques in APP/PS1 transgenic mouse brains |
ACS CHEMICAL NEUROSCIENCE
|
| 2019-06 |
Tandem [4+1+1] annulation approach to 4-acyl-3,4-dihydropyrrolo[1,2-a]pyrazines: diastereoselective construction of dihydropyrazine units from pyrroles |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2019-06 |
Design, synthesis, and biological evaluation of novel pyrrolo[1,2-a]pyrazine derivatives |
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
|
| 2019-05 |
One-Pot, Three-Component Approach to Diarylmethylphosphonates: A Direct Entry to Polycyclic Aromatic Systems |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2019-05 |
Intramolecular electrophilic cyclization approach to 6-substituted naphtho[2,1-b]benzofuran: novel dual-state emissive fluorophores with blue emission |
ACS COMBINATORIAL SCIENCE
|
| 2019-03 |
One-pot, three-component approach to diarylacetonitriles |
Organic Chemistry Frontiers
|
| 2019-01 |
Electrophilic acetylation and formylation of pyrrolo[1,2-a]pyrazines: substituent effects on regioselectivity |
ARKIVOC
|
| 2019-01 |
Convergent synthesis of diptoindonesin G |
TETRAHEDRON LETTERS
|
| 2018-12 |
Synthesis and biological evaluation of novel Ani9 derivatives as potent and selective ANO1 inhibitors |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
|
| 2018-08 |
Light-induced electrical switch via photo-responsive nanocomposite film |
SENSORS AND ACTUATORS B-CHEMICAL
|
| 2018-05 |
Development of S-methylmethionine sulfonium derivatives and their skin-protective effect against ultraviolet exposure |
BIOMOLECULES & THERAPEUTICS
|
| 2018-03 |
Mitochondria-targeting indolizino[3,2-c]quinolines as novel class of photosensitizers for photodynamic anticancer activity |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
|
| 2018-02 |
Total syntheses of biologically active pterocarpan, isoflavan, and isoflavanone from Dalbergia oliveri |
BULLETIN OF THE KOREAN CHEMICAL SOCIETY
|
| 2018-02 |
Skeletal reorganization: synthesis of diptoindonesin G from pauciflorol F |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2018-01 |
Biological evaluation of indolizine-chalcone hybrids as new anticancer agents |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
|
| 2018-01 |
Design and synthesis of a hybrid framework of indanone and chromane: total synthesis of a homoisoflavanoid, brazilane |
ORGANIC & BIOMOLECULAR CHEMISTRY
|
| 2017-11 |
Mollugin enhances the osteogenic action of BMP-2 via the p38-Smad signaling pathway |
ARCHIVES OF PHARMACAL RESEARCH
|
| 2017-11 |
Indolizino[3,2-c]quinolines as environment-sensitive fluorescent light-up probes for targeted live cell imaging |
SENSORS AND ACTUATORS B-CHEMICAL
|
| 2017-09 |
Diversity-oriented functionalization of indolizines at the C3 position via multicomponent Kabachnik-Fields reaction |
TETRAHEDRON
|
| 2017-05 |
Regiospecific synthesis of 5- and 6-acylated naphtho[1,2-b]benzofurans via intramolecular alkyne carbonyl metathesis |
SYNTHESIS-STUTTGART
|
| 2017-04 |
Polyaromatic heterocycles through intramolecular alkyne carbonyl metathesis: 5-acylnaphtho[2,1-b]benzofurans |
TETRAHEDRON
|
| 2017-04 |
Catalyst-free synthesis of 4-alkynylazobenzenes from quinols |
TETRAHEDRON LETTERS
|
| 2017-04 |
Total syntheses of urgineanins A, B, D, and their analogues |
SYNTHESIS-STUTTGART
|
| 2017-03 |
Altering the cyclization modes: temperature-dependent intramolecular 7-endo-dig vs. 6-endo-dig electrophilic ring closures |
ORGANIC LETTERS
|
| 2016-12 |
Symmetry-based approach to oligostilbenoids: Rapid entry to viniferifuran, shoreaphenol, malibatol A, and diptoindonesin G |
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
|
| 2016-11 |
Chemoselective reduction of quinols as an alternative to Sonogashira coupling: synthesis of polysubstituted benzofurans |
ORGANIC & BIOMOLECULAR CHEMISTRY
|
| 2016-09 |
Syntheses of pterocarpenes and coumestans via regioselective cyclodehydration |
ORGANIC & BIOMOLECULAR CHEMISTRY
|
| 2016-05 |
Mitochondria-targeted vitamin E protects skin from UVB-irradiation |
BIOMOLECULES & THERAPEUTICS
|
| 2016-04 |
1-(2,3-Dibenzimidazole-2-ylpropyl)-2-methoxybenzene is a Syk inhibitor with anti-inflammatory properties |
MOLECULES
|
| 2016-01 |
Synthesis of 6-Aryl-5-iodobenzo[e]pyrido[1,2-a]indoles by 6-endo-dig Iodocyclization |
ASIAN JOURNAL OF ORGANIC CHEMISTRY
|
| 2016-01 |
Synthesis, characterization and biological evaluation of anti-cancer indolizine derivatives via inhibiting β-catenin activity and activating p53 |
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
|
| 2015-12 |
Reciprocal regulation of ERα and ERβ stability and activity by diptoindonesin G |
CHEMISTRY & BIOLOGY
|
| 2015-12 |
C3 Functionalization of indolizines via In(III)-catalyzed three-component reaction |
ORGANIC & BIOMOLECULAR CHEMISTRY
|
| 2015-11 |
Alkyne Carbonyl Metathesis As a Means To Make 4-Acyl Chromenes: Synthesis of (±)-Deguelin and (±)-Munduserone |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2015-10 |
Construction of benzo-fused indolizines, pyrrolo[1,2-a]quinolines, via alkyne-carbonyl metathesis |
ORGANIC & BIOMOLECULAR CHEMISTRY
|
| 2015-09 |
Deformylative Intramolecular Hydroarylation: Synthesis of Benzo[e]pyrido[1,2-a]indoles |
ORGANIC LETTERS
|
| 2015-08 |
When Indolizine Meets Quinoline: Diversity-Oriented Synthesis of New Polyheterocycles and Their Optical Properties |
ACS COMBINATORIAL SCIENCE
|
| 2015-08 |
The Photoprotective Effect of S-Methylmethionine Sulfonium in Skin |
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
|
| 2015-04 |
A concise synthetic approach to brazilin via Pd-catalyzed allylic arylation |
ORGANIC & BIOMOLECULAR CHEMISTRY
|
| 2015-04 |
Electron-withdrawing group effect in aryl group of allyl bromides for the successful synthesis of indolizines via a novel [3+3] annulation approach |
TETRAHEDRON
|
| 2015-02 |
Total Synthesis of Brazilin |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2015-01 |
Mollugin from Rubea cordifolia suppresses receptor activator of nuclear factor-B ligand-induced osteoclastogenesis and bone resorbing activity in vitro and prevents lipopolysaccharide-induced bone loss in vivo |
PHYTOMEDICINE
|
| 2014-10 |
Diversity-oriented decoration of pyrrolo[1,2-a]pyrazines |
TETRAHEDRON
|
| 2014-07 |
Palladium-Catalyzed α-Arylation of Aryloxyketones for the Synthesis of 2,3-Disubstituted Benzofurans |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2013-10 |
Domino Knoevenagel condensation/intramolecular aldol cyclization route to diverse indolizines with densely functionalized pyridine units |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2013-02 |
Cycloaromatization Approach to Polysubstituted Indolizines from 2-Acylpyrroles: Decoration of the Pyridine Unit |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2012-09 |
Facile approach to diverse 3-acylated indolizines via a sequential Sonogashira coupling/iodocyclization process |
TETRAHEDRON
|
| 2012-07 |
Palladium-catalyzed construction of poly-substituted indolizinones |
TETRAHEDRON
|
| 2011-11 |
Anti-resorptive and Anabolic Activity of 3-(3,5-Dimethoxyphenyl)-6-methoxybenzofuran-4-carboxylate |
Bulletin of the Korean Chemical Society
|
| 2011-07 |
Effect of a mitochondria-targeted vitamin E derivative on mitochondrial alteration and systemic oxidative stress in mice |
BRITISH JOURNAL OF NUTRITION
|